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Article

Beyond the Hypercube: Evolutionary Accessibility of Fitness Landscapes with Realistic Mutational Networks.

PLoS computational biology - 1 Dec 2016

Zagorski Marcin, Burda Zdzislaw, Waclaw Bartlomiej

Abstract excerpt

Evolutionary pathways describe trajectories of biological evolution in the space of different variants of organisms (genotypes). The probability of existence and the number of evolutionary pathways that lead from a given genotype to a better-adapted genotype are important measures of accessibility of local fitness optima and the reproducibility of evolution. Both quantities have been studied in simple...

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Identifiers

PMID: 27935934
DOI: 10.1371/journal.pcbi.1005218
PMCID: PMC5147777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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