Article
Isothermal Diagnostic Assays for Monitoring Single Nucleotide Polymorphisms in Necator americanus Associated with Benzimidazole Drug Resistance.
PLoS neglected tropical diseases - 1 Dec 2016
Rashwan Nour, Bourguinat Catherine, Keller Kathy, Gunawardena Nipul Kithsiri, de Silva Nilanthi, Prichard Roger
Abstract excerpt
BACKGROUND: Soil-transmitted helminths (STHs) are the most prevalent intestinal helminths of humans, and a major cause of morbidity in tropical and subtropical countries. The benzimidazole (BZ) drugs albendazole (ABZ) and mebendazole (MBZ) are used for treatment of human STH infections and this use is increasing dramatically with massive drug donations. Frequent and prolonged use of these drugs could lead to the...
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