Article
Genomic duplication and translocation of reactivation transactivator and bZIP-homolog genes is a conserved event in alcelaphine herpesvirus 1.
Scientific reports - 7 Dec 2016
Myster Françoise, van Beurden Steven J, Sorel Océane, Suárez Nicolás M, Vanderplasschen Alain, Davison Andrew J, Dewals Benjamin G
Abstract excerpt
Alcelaphine herpesvirus 1 (AlHV-1) is a gammaherpesvirus carried asymptomatically by wildebeest. Upon cross-species transmission, AlHV-1 induces malignant catarrhal fever (MCF), a fatal lymphoproliferative disease of ruminants, including cattle. The strain C500 has been cloned as an infectious, pathogenic bacterial artificial chromosome (BAC) that is used to study MCF. Although AlHV-1 infection can be established...
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