Article
Prognostic value of rare and complex mutations in EGFR and serum levels of soluble EGFR and its ligands in non-small cell lung carcinoma patients.
Clinical biochemistry - 1 Apr 2017
Haghgoo Seyyed Mortaza, Khosravi Adnan, Mortaz Esmaeil, Pourabdollah-Toutkaboni Mihan, Seifi Sharareh, Sabour Siamak, Allameh Abdolamir
Abstract excerpt
BACKGROUND: A number of complex and rare mutations in epidermal growth factor receptor (EGFR) gene have been identified and the clinical implication of serum EGFR ligands has also been reported. However, the prognostic significance of these mutations and also the serum EGFR and its ligands in Non-Small Cell Lung Carcinoma (NSCLC) has remained a challenging issue. This study is aimed at finding the prognostic...
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