Article
Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism.
Journal of prosthodontic research - 1 Jul 2017
Hoashi Yurie, Okamoto Satoshi, Abe Yuka, Matsumoto Takashi, Tanaka Junichi, Yoshida Yuya, Imaizumi Kent, Mishima Kenji, Akamatsu Wado, Okano Hideyuki, Baba Kazuyoshi
Abstract excerpt
PURPOSE: Sleep bruxism (SB) is classified as a sleep-related movement disorder characterized by grinding and clenching of the teeth during sleep, which is responsible for a variety of clinical problems such as abnormal tooth attrition and fracture of teeth or roots. Little is known about the etiology of SB. Our previous study identified a genomic association of the serotonin 2A receptor (5-HT2A) single nucleotide...
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