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Article

Analysis of genetic polymorphisms and mRNA expression of DRD3 and HTR2A in bruxism.

BMC oral health - 3 Jun 2026

Gassara Yosra, Foddha Hajer, Chouchene Saoussen, Nasri Sarra, Kallala Rim, Haj Khelil Amel, Hassin Mohsen, Ben Abdennebi Hassen, Harzallah Belhassen

Abstract excerpt

BACKGROUND: Bruxism, characterized by the involuntary grinding or clenching of teeth, is influenced by genetic, psychological, and environmental factors. This study aimed to evaluate the role of DRD3 (rs6280) and HTR2A (rs6313) polymorphisms in bruxism and to investigate the expression of these genes to better understand their biological significance. METHODS: This case-control study included 82 bruxism patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42237294
DOI: 10.1186/s12903-026-08633-8
PMCID: PMC13505174

Genes

HTR2A
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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