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Article

Systematic ajmaline challenge in patients with long QT 3 syndrome caused by the most common mutation: a multicentre study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 1 Oct 2017

Hohmann Stephan, Rudic Boris, Konrad Torsten, Duncker David, König Thorben, Tülümen Erol, Rostock Thomas, Borggrefe Martin, Veltmann Christian

Abstract excerpt

AIMS: Overlap syndromes of long QT 3 syndrome (LQT3) and the Brugada syndrome (BrS) have been reported. Identification of patients with an overlapping phenotype is crucial before initiation of Class I antiarrhythmic drugs for LQT3. Aim of the present study was to elucidate the yield of ajmaline challenge in unmasking the Brugada phenotype in patients with LQT3 caused by the most common mutation, SCN5A-E1784K....

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PMID: 27915266
DOI: 10.1093/europace/euw214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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