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Computational modelling of amino acid transfer interactions in the placenta

24 Apr 2010

Abstract excerpt

Amino acid transfer from mother to fetus via the placenta plays a critical role in normal development, and restricted transfer is associated with fetal growth restriction. Placental amino acid transfer involves the interaction of 15 or more transporters and 20 amino acids. This complexity means that knowing which transporters are present is not sufficient to predict how they operate together as a system....

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PMID: 20418347
DOI: 10.1113/expphysiol.2010.052902

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