Article
The impact of interferon-alpha2 on HLA genes in patients with polycythemia vera and related neoplasms.
Leukemia & lymphoma - 1 Aug 2017
Skov Vibe, Riley Caroline Hasselbalch, Thomassen Mads, Kjær Lasse, Stauffer Larsen Thomas, Bjerrum Ole Weis, Kruse Torben A, Hasselbalch Hans Carl
Abstract excerpt
Gene expression profiling in Philadelphia-negative chronic myeloproliferative neoplasms (MPNs) have unraveled significant deregulation of several immune and inflammation genes of potential importance for clonal evolution. Other mechanisms might be downregulation of major histocompatibility class I and II genes used by tumor cells to escape antitumor T-cell-mediated immune responses. Several genes encoding human...
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