Article
Molecular responses and chromosomal aberrations in patients with polycythemia vera treated with peg-proline-interferon alpha-2b.
American journal of hematology - 1 Apr 2015
Them Nicole C C, Bagienski Klaudia, Berg Tiina, Gisslinger Bettina, Schalling Martin, Chen Doris, Buxhofer-Ausch Veronika, Thaler Josef, Schloegl Ernst, Gastl Guenther A, Wolf Dominik, Strecker Karin, Egle Alexander, Melchardt Thomas, Burgstaller Sonja, Willenbacher Ella, Zagrijtschuk Oleh, Klade Christoph, Greil Richard, Gisslinger Heinz, Kralovics Robert
Abstract excerpt
Fifty-one polycythemia vera (PV) patients were enrolled in the phase I/II clinical study PEGINVERA to receive a new formulation of pegylated interferon alpha (peg-proline-IFNα-2b, AOP2014/P1101). Peg-proline-IFNα-2b treatment led to high response rates on both hematologic and molecular levels. He...
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