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Article

EGFR Mutation Subtypes Influence Survival Outcomes following First-Line Gefitinib Therapy in Advanced Asian NSCLC Patients.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Mar 2017

Sutiman Natalia, Tan Shao Weng, Tan Eng Huat, Lim Wan Teck, Kanesvaran Ravindran, Ng Quan Sing, Jain Amit, Ang Mei Kim, Tan Wan Ling, Toh Chee Keong, Chowbay Balram

Abstract excerpt

INTRODUCTION: Activating mutations in the EGFR gene have been shown to confer sensitivity to EGFR tyrosine kinase inhibitors in patients with advanced NSCLC. However, wide interpatient variability in treatment outcomes in response to EGFR tyrosine kinase inhibitors in these patients remains unaccounted for. This study aimed to evaluate the influence of EGFR mutation types and subtypes on survival outcomes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27908825
DOI: 10.1016/j.jtho.2016.11.2225

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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