Article
Phylogenetic and population-based approaches to mitogenome variation do not support association with male infertility.
Journal of human genetics - 1 Mar 2017
Gómez-Carballa Alberto, Pardo-Seco Jacobo, Martinón-Torres Federico, Salas Antonio
Abstract excerpt
Infertility has a complex multifactorial etiology and a high prevalence worldwide. Several studies have pointed to variation in the mitochondrial DNA (mtDNA) molecule as a factor responsible for the different disease phenotypes related to infertility. We analyzed 53 mitogenomes of infertile males from Galicia (northwest Spain), and these haplotypes were meta-analyzed phylogenetically with 43 previously reported...
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