Article
Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients.
PLoS pathogens - 1 Nov 2016
Schwartbeck Bianca, Birtel Johannes, Treffon Janina, Langhanki Lars, Mellmann Alexander, Kale Devika, Kahl Janina, Hirschhausen Nina, Neumann Claudia, Lee Jean C, Götz Friedrich, Rohde Holger, Henke Hanae, Küster Peter, Peters Georg, Kahl Barbara C
Abstract excerpt
Cystic fibrosis (CF) is associated with chronic bacterial airway infections leading to lung insufficiency and decreased life expectancy. Staphylococcus aureus is one of the most prevalent pathogens isolated from the airways of CF patients. Mucoid colony morphology has been described for Pseudomonas aeruginosa, the most common pathogen in CF, but not for S. aureus. From the airways of 8 of 313 CF patients (2.5%)...
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