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Article

Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp.

PloS one - 1 Jan 2016

Bender Jennifer K, Fleige Carola, Klare Ingo, Fiedler Stefan, Mischnik Alexander, Mutters Nico T, Dingle Kate E, Werner Guido

Abstract excerpt

The National Reference Centre for Staphylococci and Enterococci in Germany has received an increasing number of clinical linezolid-resistant E. faecium isolates in recent years. Five isolates harbored a cfr(B) variant gene locus the product of which is capable of conferring linezolid resistance. The cfr(B)-like methyltransferase gene was also detected in Clostridium difficile. Antimicrobial susceptibility was...

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Identifiers

PMID: 27893790
DOI: 10.1371/journal.pone.0167042
PMCID: PMC5125667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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