Article
Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota.
Nature biotechnology - 1 Jan 2017
Magnúsdóttir Stefanía, Heinken Almut, Kutt Laura, Ravcheev Dmitry A, Bauer Eugen, Noronha Alberto, Greenhalgh Kacy, Jäger Christian, Baginska Joanna, Wilmes Paul, Fleming Ronan M T, Thiele Ines
Abstract excerpt
Genome-scale metabolic models derived from human gut metagenomic data can be used as a framework to elucidate how microbial communities modulate human metabolism and health. We present AGORA (assembly of gut organisms through reconstruction and analysis), a resource of genome-scale metabolic reconstructions semi-automatically generated for 773 human gut bacteria. Using this resource, we identified a defined...
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