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Article

Direct regulation of FOXK1 by C-jun promotes proliferation, invasion and metastasis in gastric cancer cells.

Cell death & disease - 24 Nov 2016

Peng Ying, Zhang Pei, Huang Xiaoting, Yan Qingqing, Wu Meiyan, Xie Ruyi, Wu Yao, Zhang Mengnan, Nan Qingzhen, Zhao Jinjun, Li Aimin, Xiong Jing, Ren Yuexin, Bai Yang, Chen Ye, Liu Side, Wang Jide

Abstract excerpt

Forkhead box (FOX) K1 is a member of the FOX transcription factor superfamily. High FOXK1 expression is associated with several cancers. However, whether FOXK1 expression contributes to gastric cancer (GC) development and progression remains unknown. We analyzed the FOXK1 promoter using the Promo software and found several binding sequence transcription factors, including c-jun. However, the molecular mechanism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27882939
DOI: 10.1038/cddis.2016.225
PMCID: PMC5260906

Genes

FOXK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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