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Tank-Binding Kinase 1 (TBK1) Gene and Open-Angle Glaucomas (An American Ophthalmological Society Thesis).

Transactions of the American Ophthalmological Society - 1 Aug 2016

Fingert John H, Robin Alan L, Scheetz Todd E, Kwon Young H, Liebmann Jeffrey M, Ritch Robert, Alward Wallace L M

Abstract excerpt

PURPOSE: To investigate the role of TANK-binding kinase 1 (TBK1) gene copy-number variations (ie, gene duplications and triplications) in the pathophysiology of various open-angle glaucomas. METHODS: In previous studies, we discovered that copy-number variations in the TBK1 gene are associated with normal-tension glaucoma. Here, we investigated the prevalence of copy-number variations in cohorts of patients with...

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Identifiers

PMID: 27881886
PMCID: PMC5113957

Genes

TBK1
TANK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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