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Article

A method to customize population-specific arrays for genome-wide association testing.

European journal of human genetics : EJHG - 1 Feb 2017

Ehli Erik A, Abdellaoui Abdel, Fedko Iryna O, Grieser Charlie, Nohzadeh-Malakshah Sahar, Willemsen Gonneke, de Geus Eco Jc, Boomsma Dorret I, Davies Gareth E, Hottenga Jouke J

Abstract excerpt

As an example of optimizing population-specific genotyping assays using a whole-genome sequence reference set, we detail the approach that followed to design the Axiom-NL array which is characterized by an improved imputation backbone based on the Genome of the Netherlands (GoNL) reference sequence and, compared with earlier arrays, a more comprehensive inclusion of SNPs on chromosomes X, Y, and the mitochondria....

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Identifiers

PMID: 27876820
DOI: 10.1038/ejhg.2016.152
PMCID: PMC5255952

Genes

APOE
FTO
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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