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Article

The adverse impact of obesity on heart rate variability is modified by a NFE2L2 gene variant: The SAPALDIA cohort.

International journal of cardiology - 1 Feb 2017

Adam Martin, Imboden Medea, Schaffner Emmanuel, Boes Eva, Kronenberg Florian, Pons Marco, Bettschart Robert, Barthelemy Jean-Claude, Schindler Christian, Probst-Hensch Nicole

Abstract excerpt

BACKGROUND: Overweight has been associated with an increase in inflammatory markers and with an imbalance in the autonomic nervous system, such as a decrease in heart rate variability (HRV). In this study we aimed to investigate the modifying effect of a genetic variation in a major anti-inflammatory marker gene, NFE2L2, on the relationship between overweight and HRV. METHODS: We analyzed participants of the...

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Identifiers

PMID: 27866025
DOI: 10.1016/j.ijcard.2016.11.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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