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Article

Forkhead box P3 regulates ARHGAP15 expression and affects migration of glioma cells through the Rac1 signaling pathway.

Cancer science - 1 Jan 2017

Sun Zhen, Zhang Biao, Wang Chen, Fu Tao, Li Lianling, Wu Qiaoli, Cai Ying, Wang Jinhuan

Abstract excerpt

Forkhead box P3 (FOXP3) plays a crucial role in the development and function of regulatory T cells and was recently identified as a tumor suppressor in different cancer types. Forkhead box P3 is expressed in normal brain tissues, but is strongly downregulated or absent in glioblastomas. In order to understand the FOXP3 adjustment mechanisms in glioma cells, we performed a DNA microarray in U87 cells...

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Share to Epithelial-Mesenchymal Transition
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27862679
DOI: 10.1111/cas.13118
PMCID: PMC5276829

Genes

FOXP3
ARHGAP15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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