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Article

Association of the KLK1 rs5516 G allele and the ACE D allele with aortic aneurysm and atherosclerotic stenosis.

Medicine - 1 Nov 2016

Zhang Yiming, Huang Hongliang, Ma Yuliang, Sun Yifeng, Wang Guohua, Tang Liming

Abstract excerpt

OBJECTIVE: Atherosclerosis underlies aortic aneurysm (AA) and atherosclerotic stenosis (AS). Kallikrein-1 (KLK1) and angiotensin-converting enzyme (ACE) are 2 key molecules in kallikrein-kinin systems and renin-angiotensin systems, respectively, which are responsible for maintaining vascular balance and stability, playing important roles in atherosclerosis. We aimed to assess the involvement of single nucleotide...

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Source

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Identifiers

PMID: 27858843
DOI: 10.1097/MD.0000000000005120
PMCID: PMC5591091

Genes

ACE
KLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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