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Article

Association of a TFAM haplotype with aggressive prostate cancer in overweight or obese Mexican Mestizo men.

Urologic oncology - 1 Mar 2017

Granados Jesús Benítez, Méndez Juan Pablo, Feria-Bernal Guillermo, García-García Eduardo, Tejeda María Elena, Rojano-Mejía David, Tapia André, Canto Patricia

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction has been associated with the development of cancer and obesity, being prostate cancer more aggressive in obese men. It has been suggested that the mitochondrial transcription factor A (TFAM) plays a central role in these events. OBJECTIVE: The aim of this study was to analyze the possible association of 3 TFAM polymorphisms, as well as their haplotypes, with the development...

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Source

Identifiers

PMID: 27843028
DOI: 10.1016/j.urolonc.2016.10.011

Genes

TFAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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