Article
Treatment With Ledipasvir-Sofosbuvir for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic Hepatitis C Virus Genotype 1 or 4 Infection: A Randomized Trial.
Annals of internal medicine - 17 Jan 2017
Colombo Massimo, Aghemo Alessio, Liu Hong, Zhang Jie, Dvory-Sobol Hadas, Hyland Robert, Yun Chohee, Massetto Benedetta, Brainard Diana M, McHutchison John G, Bourlière Marc, Peck-Radosavljevic Markus, Manns Michael, Pol Stanislas
Abstract excerpt
BACKGROUND: Use of interferon and ribavirin to treat chronic hepatitis C virus (HCV) infection in kidney transplant recipients is limited because of the risk for allograft rejection and poor tolerability. OBJECTIVE: To evaluate the safety and efficacy of the interferon- and ribavirin-free regimen ledipasvir-sofosbuvir in kidney transplant recipients with chronic genotype 1 or 4 HCV infection. DESIGN: Randomized,...
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