Article
X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis.
International journal of molecular sciences - 8 Nov 2016
Khalifa Olfa, Pers Yves-Marie, Ferreira Rosanna, Sénéchal Audrey, Jorgensen Christian, Apparailly Florence, Duroux-Richard Isabelle
Abstract excerpt
Rheumatoid arthritis (RA) is an autoimmune disease that predominantly affects women. MicroRNAs have emerged as crucial regulators of the immune system, whose expression is deregulated in RA. We aimed at quantifying the expression level of 14 miRNAs located on the X chromosome and at identifying whether differences are associated with disease and/or sex. A case-control study of 21 RA patients and 22 age- and...
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