Article
The effect of collagen hydrogel on 3D culture of ovarian follicles.
Biomedical materials (Bristol, England) - 11 Nov 2016
Joo Sunyoung, Oh Seh-Hoon, Sittadjody Sivanandane, Opara Emmanual C, Jackson John D, Lee Sang Jin, Yoo James J, Atala Anthony
Abstract excerpt
The in vivo function and phenotype of ovarian follicle cells are determined by many factors. When these cells are removed from the in vivo microenvironment and grown in a 2D in vitro environment, the function of the follicular cells is difficult to preserve. A collagen hydrogel was used to examine the hormone and oocyte maturation of ovary follicles in a 3D culture system. Ovarian follicles from rats were...
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