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Article

Establishing RNAi in a Non-Model Organism: The Antarctic Nematode Panagrolaimus sp. DAW1.

PloS one - 1 Jan 2016

Seybold Anna C, Wharton David A, Thorne Michael A S, Marshall Craig J

Abstract excerpt

The Antarctic nematode Panagrolaimus sp. DAW1 is one of the only organisms known to survive extensive intracellular freezing throughout its tissues. Although the physiological mechanisms of this extreme adaptation are partly understood, the molecular mechanisms remain largely unknown. RNAi is a method that allows the examination of gene function in a direct, targeted manner, by knocking out specific mRNAs and...

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PMID: 27832164
DOI: 10.1371/journal.pone.0166228
PMCID: PMC5104476

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