Article
Longitudinal Changes in Audiometric Phenotypes of Age-Related Hearing Loss.
Journal of the Association for Research in Otolaryngology : JARO - 1 Apr 2017
Vaden Kenneth I, Matthews Lois J, Eckert Mark A, Dubno Judy R
Abstract excerpt
Presbyacusis, or age-related hearing loss, can be characterized in humans as metabolic and sensory phenotypes, based on patterns of audiometric thresholds that were established in animal models. The metabolic phenotype is thought to result from deterioration of the cochlear lateral wall and reduced endocochlear potential that decreases cochlear amplification and produces a mild, flat hearing loss at lower...
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