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Article

Targeting cell adhesion and homing as strategy to cure Waldenström's macroglobulinemia.

Best practice & research. Clinical haematology - 1 Jun 2016

Pals Steven T, Kersten Marie José, Spaargaren Marcel

Abstract excerpt

Most B-cell malignancies strictly depend on signals from the microenvironment for their survival and proliferation. This niche-dependency can be regarded as their Achilles' heel and provides an excellent target for therapy. Waldenström's macroglobulinemia (WM) is characterized by the accumulation of neoplastic post-germinal center B cells within the bone marrow (BM). Interestingly, one third of the patients carry...

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Share to Bone Marrow
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Antigen, B-Cell

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Source

Identifiers

PMID: 27825462
DOI: 10.1016/j.beha.2016.08.019

Genes

BCR
BTK
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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