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Bruton Tyrosine Kinase Inhibition: an Effective Strategy to Manage Waldenström Macroglobulinemia.

Current hematologic malignancy reports - 1 Jun 2024

Tawfiq Reema K, Abeykoon Jithma P, Kapoor Prashant

Abstract excerpt

PURPOSE OF REVIEW: The treatment of Waldenström macroglobulinemia (WM) has evolved over the past decade. With the seminal discoveries of MYD88 and CXCR warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) mutations in WM cells, our understanding of the disease biology and treatment has improved. The development of a new class of agents, Bruton tyrosine kinase inhibitors (BTKi), has substantially...

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PMID: 38536576
DOI: 10.1007/s11899-024-00731-0

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