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DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.

Autoimmunity - 1 Dec 2016

Saeki Minori, Watanabe Mikio, Inoue Naoya, Tokiyoshi Ena, Takuse Yukina, Arakawa Yuya, Hidaka Yoh, Iwatani Yoshinori

Abstract excerpt

Dicer and Drosha are RNase III enzymes that are necessary for the biogenesis of most miRNAs. However, there are no reports on the association of Dicer and Drosha with the pathogenesis of autoimmune thyroid disease (AITD). We genotyped DICER rs3742330A/G and rs1057035T/C as well as DROSHA rs644236C/T and rs10719C/T polymorphisms in 255 Hashimoto's disease (HD) patients, in 255 Graves' disease (GD) patients and in...

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Source

Identifiers

PMID: 27808570
DOI: 10.1080/08916934.2016.1230846

Genes

DROSHA

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