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Directional and reoccurring sequence change in zoonotic RNA virus genomes visualized by time-series word count

3 Nov 2016

Abstract excerpt

Ebolavirus, MERS coronavirus and influenza virus are zoonotic RNA viruses, which mutate very rapidly. Viral growth depends on many host factors, but human cells may not provide the ideal growth conditions for viruses invading from nonhuman hosts. The present time-series analyses of short and long oligonucleotide compositions in these genomes showed directional changes in their composition after invasion from a...

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PMID: 27808119
DOI: 10.1038/srep36197

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