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Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines

27 Oct 2016

Abstract excerpt

Bluetongue virus (BTV) is endemic in many parts of the world, often causing severe hemorrhagic disease in livestock. To date, at least 27 different serotypes have been recognized. Vaccination against all serotypes is necessary to protect susceptible animals and to prevent onward spread of the virus by insect vectors. In our previous studies, we generated replication-deficient (disabled infectious single-cycle...

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PMID: 27795442
DOI: 10.1128/jvi.01892-16

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