Article
Rescue of recent virulent and avirulent field strains of bluetongue virus by reverse genetics.
PloS one - 1 Jan 2012
van Gennip René G P, van de Water Sandra G P, Potgieter Christiaan A, Wright Isabel M, Veldman Daniel, van Rijn Piet A
Abstract excerpt
Since 1998, Bluetongue virus (BTV)-serotypes 1, 2, 4, 9, and 16 have invaded European countries around the Mediterranean Basin. In 2006, a huge BT-outbreak started after incursion of BTV-serotype 8 (BTV8) in North-Western Europe. More recently, BTV6 and BTV11 were reported in North-Western Europe in 2008. These latter strains are closely related to live-attenuated vaccine, whereas BTV8 is virulent and can induce...
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