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Article

Ledipasvir/sofosbuvir with or without ribavirin for the treatment of chronic hepatitis C genotype 1: A pairwise meta-analysis.

Journal of gastroenterology and hepatology - 1 Apr 2017

Ferreira Vinicius L, Assis Jarek Nayara A, Tonin Fernanda S, Borba Helena H L, Wiens Astrid, Muzzillo Dominique A, Pontarolo Roberto

Abstract excerpt

BACKGROUND AND AIM: Ledipasvir with sofosbuvir (LED/SOF) for the treatment of patients infected with genotype 1 hepatitis C virus can be used with or without ribavirin (RBV). RBV is well known to promote significant adverse events (AE). The aim of this study was to compare the efficacy and safety of treatment with LED/SOF, with or without RBV, in patients infected with hepatitis C virus genotype 1. METHODS: We...

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Identifiers

PMID: 27785825
DOI: 10.1111/jgh.13620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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