Article
Efficacy and Safety of Ledispavir/Sofosbuvir with or without Ribavirin in patients with Decompensated Liver Cirrhosis and Hepatitis C Infection: a Cohort Study.
Journal of gastrointestinal and liver diseases : JGLD - 9 Sept 2020
Gheorghe Liliana Simona, Preda Carmen, Iliescu Laura, Istratescu Doina, Chifulescu Andreea Elena, Pop Corina Silvia, Trifan Anca, Stanciu Carol, Diculescu Mircea, Voiosu Theodor, Baicus Cristian, Tugui Letitia, Iacob Speranta, Tieranu Cristian, Meianu Corina, Manuc Mircea
Abstract excerpt
BACKGROUND AND AIMS: Ledipasvir/Sofosbuvir (LDV/SOF) with or without Ribavirin (RBV) has shown good results in terms of efficacy and safety in clinical trials in advanced liver cirrhosis, but real-life data are still needed in order to confirm this profile. We investigated the efficacy and safety of LDV/SOF in a large Romanian population with liver cirrhosis and genotype 1b hepatitis C virus (HCV). METHODS: We...
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