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Article

Transcription factor ETV1 is essential for rapid conduction in the heart

23 Oct 2016

Abstract excerpt

Rapid impulse propagation in the heart is a defining property of pectinated atrial myocardium (PAM) and the ventricular conduction system (VCS) and is essential for maintaining normal cardiac rhythm and optimal cardiac output. Conduction defects in these tissues produce a disproportionate burden of arrhythmic disease and are major predictors of mortality in heart failure patients. Despite the clinical importance,...

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PMID: 27775552
DOI: 10.1172/jci87968

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