Article
Comparison of Standardization Methods for the Harmonization of Phenotype Data: An Application to Cognitive Measures.
American journal of epidemiology - 15 Nov 2016
Griffith Lauren E, van den Heuvel Edwin, Raina Parminder, Fortier Isabel, Sohel Nazmul, Hofer Scott M, Payette Hélène, Wolfson Christina, Belleville Sylvie, Kenny Meghan, Doiron Dany
Abstract excerpt
Standardization procedures are commonly used to combine phenotype data that were measured using different instruments, but there is little information on how the choice of standardization method influences pooled estimates and heterogeneity. Heterogeneity is of key importance in meta-analyses of observational studies because it affects the statistical models used and the decision of whether or not it is...
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