Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study.

doi:10.18632/oncotarget.12714

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Article

Targeted NGS, array-CGH, and patient-derived tumor xenografts for precision medicine in advanced breast cancer: a single-center prospective study.

Oncotarget - 29 Nov 2016

Gonçalves Anthony, Bertucci François, Guille Arnaud, Garnier Severine, Adelaide José, Carbuccia Nadine, Cabaud Oliver, Finetti Pascal, Brunelle Serge, Piana Gilles, Tomassin-Piana Jeanne, Paciencia Maria, Lambaudie Eric, Popovici Cornel, Sabatier Renaud, Tarpin Carole, Provansal Magali, Extra Jean-Marc, Eisinger François, Sobol Hagay, Viens Patrice, Lopez Marc, Ginestier Christophe, Charafe-Jauffret Emmanuelle, Chaffanet Max, Birnbaum Daniel

Abstract excerpt

BACKGROUND: Routine feasibility and clinical impact of genomics-based tumor profiling in advanced breast cancer (aBC) remains to be determined. We conducted a pilot study to evaluate whether precision medicine could be prospectively implemented for aBC patients in a single center and to examine whether patient-derived tumor xenografts (PDX) could be obtained in this population. RESULTS: Thirty-four aBC patients...

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PMID: 27765906
DOI: 10.18632/oncotarget.12714
PMCID: PMC5346725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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