Article
Network meta-analysis of first- and second-generation protease inhibitors for chronic hepatitis C genotype 1: efficacy based on RVR and SVR 24.
European journal of clinical pharmacology - 1 Jan 2017
Borba Helena H, Wiens Astrid, Steimbach Laiza M, Perlin Cassio M, Tonin Fernanda S, Pedroso Maria L A, Fernandez-Llimos Fernando, Pontarolo Roberto
Abstract excerpt
PURPOSE: This study aimed to compare the efficacy among direct-acting antiviral agents (first and second-generation direct-acting antiviral agents (DAAs)) with placebo and with standard dual therapy (pegylated interferon + ribavirin (Peg-IFN + RBV)) in terms of rapid virologic response (RVR) and sustained virologic response (SVR) in chronic hepatitis C genotype 1 treatment. METHODS: We performed a systematic...
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