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Article

Network meta-analysis of direct-acting antivirals in combination with peginterferon-ribavirin for previously untreated patients with hepatitis C genotype 1 infection.

QJM : monthly journal of the Association of Physicians - 1 Apr 2015

Druyts E, Lorenzi M, Toor K, Thorlund K, Mills E J

Abstract excerpt

AIM: To conduct a network meta-analysis (NMA) to determine the comparative efficacy, as measured by sustained virological response (SVR), between boceprevir (BOC), telaprevir (TEL), faldaprevir (FAL), simeprevir (SIM) and sofosbuvir (SOF) in combination with peginterferon-ribavirin (PR) against a control of PR. DESIGN: A literature search was conducted to identify randomized controlled trials (RCTs) including...

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PMID: 25239762
DOI: 10.1093/qjmed/hcu202

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BOC

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