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Article

Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.

Cancer prevention research (Philadelphia, Pa.) - 1 Jan 2017

Mallery Susan R, Wang Daren, Santiago Brian, Pei Ping, Schwendeman Steven P, Nieto Kari, Spinney Richard, Tong Meng, Koutras George, Han Brian, Holpuch Andrew, Lang James

Abstract excerpt

Over one third of patients who have undergone oral squamous cell carcinoma (OSCC) surgical resections develop life-threatening and often untreatable recurrences. A variety of drugs, intended for management of recurrent or disseminated cancers, were designed to exploit cancer cells' reliance upon overexpressed receptors and gratuitous signaling. Despite their conceptual promise, clinical trials showed these agents...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27756753
DOI: 10.1158/1940-6207.CAPR-16-0180
PMCID: PMC5222683

Genes

HPR
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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