Article
Effects of epidermal growth factor receptor-tyrosine kinase inhibitors alone on EGFR-mutant non-small cell lung cancer with brain metastasis.
Thoracic cancer - 1 Nov 2016
Zhang Qiuyi, Zhang Xuchao, Yan Honghong, Jiang Benyuan, Xu Chongrui, Yang Jinji, Chen Zhihong, Su Jian, Wu Yi-Long, Zhou Qing
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are remarkably effective for treating EGFR-mutant non-small cell lung cancer (NSCLC). However, the individual role of EGFR-TKIs in patients with brain metastasis (BM) arising from EGFR-mutant NSCLC remains unclear. METHODS: Patients with BM secondary to NSCLC and harboring EGFR-activating mutations were retrospectively screened....
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