Article
Streptococcus mutans copper chaperone, CopZ, is critical for biofilm formation and competitiveness.
Molecular oral microbiology - 1 Dec 2016
Garcia S S, Du Q, Wu H
Abstract excerpt
The oral cavity is a dynamic environment characterized by hundreds of bacterial species, saliva, and an influx of nutrients and metal ions such as copper. Although there is a physiologic level of copper in the saliva, the oral cavity is often challenged with an influx of copper ions. At high concentrations copper is toxic and must therefore be strictly regulated by pathogens for them to persist and cause disease....
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