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Biomarkers for immune therapy in colorectal cancer: mismatch-repair deficiency and others

1 Oct 2016

Abstract excerpt

Colorectal cancer (CRC) is a heterogeneous disease for which the treatment backbone has primarily been cytotoxic chemotherapy. With better understanding of the involved molecular mechanisms, it is now known that there are a number of epigenetic and genetic events, which are involved in CRC pathogenesis. Specific biomarkers have been identified which can be used to determine the clinical outcome of patients beyond...

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PMID: 27747085
DOI: 10.21037/jgo.2016.07.03

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