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Article

Associations between genetic risk, functional brain network organization and neuroticism.

Brain imaging and behavior - 1 Dec 2017

Servaas Michelle N, Geerligs Linda, Bastiaansen Jojanneke A, Renken Remco J, Marsman Jan-Bernard C, Nolte Ilja M, Ormel Johan, Aleman André, Riese Harriëtte

Abstract excerpt

Neuroticism and genetic variation in the serotonin-transporter (SLC6A4) and catechol-O-methyltransferase (COMT) gene are risk factors for psychopathology. Alterations in the functional integration and segregation of neural circuits have recently been found in individuals scoring higher on neuroticism. The aim of the current study was to investigate how genetic risk factors impact functional network organization...

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Identifiers

PMID: 27743374
DOI: 10.1007/s11682-016-9626-2
PMCID: PMC5707236

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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