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Article

Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma

12 Oct 2016

Abstract excerpt

BACKGROUND: This study addresses involvement of major 5-fluorouracil (5-FU) pathway genes in the prognosis of colorectal carcinoma patients. METHODS: Testing set and two validation sets comprising paired tumor and adjacent mucosa tissue samples from 151 patients were used for transcript profiling of 15 5-FU pathway genes by quantitative real-time PCR and DNA methylation profiling by high resolution melting...

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PMID: 27733154
DOI: 10.1186/s12885-016-2826-8

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