Single-nucleotide polymorphism rs4142441 and MYC co-modulated long non-coding RNA OSER1-AS1 suppresses non-small cell lung cancer by sequestering ELAVL1.

doi:10.1111/cas.14713

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Article

Single-nucleotide polymorphism rs4142441 and MYC co-modulated long non-coding RNA OSER1-AS1 suppresses non-small cell lung cancer by sequestering ELAVL1.

Cancer science - 1 Jun 2021

Xie Weijia, Wang Youhao, Zhang Yao, Xiang Ying, Wu Na, Wu Long, Li Chengying, Cai Tongjian, Ma Xiangyu, Yu Zubin, Bai Li, Li Yafei

Abstract excerpt

Single-nucleotide polymorphisms (SNP) and long non-coding RNAs (lncRNAs) have been involved in the process of lung cancer. Following clues given by lung cancer risk-associated SNP, we aimed to find novel functional lncRNAs as candidate targets in lung cancer. We identified a lncRNA Oxidative Stress Responsive Serine Rich 1 Antisense RNA 1 (OSER1-AS1) through a lung cancer risk-associated SNP rs4142441. OSER1-AS1...

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Identifiers

PMID: 33113263
DOI: 10.1111/cas.14713
PMCID: PMC8177763

Genes

OSER1
ELAVL1
MYC

Provenance

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