Article
RelB/NF-κB links cell cycle transition and apoptosis to endometrioid adenocarcinoma tumorigenesis.
Cell death & disease - 6 Oct 2016
Ge Qiu-Lin, Liu San-Hong, Ai Zhi-Hong, Tao Min-Fang, Ma Li, Wen Shan-Yun, Dai Miao, Liu Fei, Liu Han-Shao, Jiang Rong-Zhen, Xue Zhuo-Wei, Jiang Yu-Hang, Sun Xiao-Hua, Hu Yi-Ming, Zhao Yong-Xu, Chen Xi, Tao Yu, Zhu Xiao-Lu, Ding Wen-Jing, Yang Bing-Qing, Liu Dan-Dan, Zhang Xiao-Ren, Teng Yin-Cheng
Abstract excerpt
Dysfunction of nuclear factor-κB (NF-κB) signaling has been causally associated with numerous human malignancies. Although the NF-κB family of genes has been implicated in endometrial carcinogenesis, information regarding the involvement of central regulators of NF-κB signaling in human endometrial cancer (EC) is limited. Here, we investigated the specific roles of canonical and noncanonical NF-κB signaling in...
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