Article
Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants.
Behavior genetics - 1 Jan 2017
Gerlai Robert, Poshusta Tanya L, Rampersad Mindy, Fernandes Yohaan, Greenwood Tammy M, Cousin Margot A, Klee Eric W, Clark Karl J
Abstract excerpt
The zebrafish enjoys several advantages over other model organisms. It is small, easy to maintain, prolific, and numerous genetic tools are available for it. For example, forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to cancer. However, despite its sophisticated behavioral repertoire, behavioral methods have rarely...
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