Article
The pertussis hypothesis: Bordetella pertussis colonization in the pathogenesis of Alzheimer's disease.
Immunobiology - 1 Feb 2017
Rubin Keith, Glazer Steven
Abstract excerpt
While a number of endogenous risk factors including age and genetics are established for Alzheimer's disease (AD), identification of acquired, potentially preventable or treatable causes, remains limited. In this paper, we review three epidemiologic case studies and present extensive biologic, immunologic and anatomic evidence to support a novel hypothesis that Bordetella pertussis (BP), the bacterium better...
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